Barkley was injured when he appeared to step on Cowboys defensive back Jourdan Lewis’ foot when trying to catch a pass from Daniel Jones that was off the mark. Barkley immediately knew something was wrong and limped off the field.
The Giants initially said Barkley was questionable to return but minutes later ruled him out. The FOX broadcast showed Barkley’s left ankle swollen.
Barkley had just come back from a torn ACL he suffered in the second week of the 2020 season and appeared to be fully healthy after a dominant performance in an upset win over the New Orleans Saints last week. The latest injury is a bad break for the star running back who won the 2018 Offensive Rookie of the Year and has recently run into a spate of injuries that have hampered him the last few years.
Through four games, he had recorded 186 rushing yards and two rushing touchdowns along with 14 catture per 130 yards and a receiving touchdown.
New York was also without wide receivers Sterling Shepard and Darius Slayton and offensive lineman Andrew Thomas entering the Cowboys game.