The Americans were one win away from matching the longest home streak in team history, set from April 1993 to February 1996.
They are still unbeaten in 61 matches at home, which includes 55 wins and six draws. It was the first time in 60 games on home soil that the team failed to score.
It was the first of two matches against South Korea. The teams meet again on Tuesday in St. Paul, Minnesota.
Goalkeeper Yoon Young-geul made eight saves, including a shot in the 76th minute from Carli Lloyd, who was making her 315th appearance with the team.
Before the game, U.S. Soccer honored Lindsey Horan for her 100th appearance with the team — which she played in Tokyo at the Olympics. Horan was also named captain for the match.
The United States was dealing with a number of injuries. Andi Sullivan didn’t play because of a minor knee injury announced before the game. Julie Ertz, Alyssa Naeher and Sam Mewis were in camp but unavailable because of previous injuries. Crystal Dunn and Christen Press opted out of the matches.
The match at Children’s Mercy Park was a sellout with 18,467 in attendance.
Next week’s match will be Lloyd’s last with the team. She announced her retirement following the Tokyo Games, where the United States won the bronze medal.
The U.S. had won all 13 previous matches against South Korea.